Penicillamine in seronegative polyarthritis.
نویسندگان
چکیده
منابع مشابه
Hashimoto's thyroiditis and polyarthritis: a possible subset of seronegative polyarthritis.
Fifteen patients presenting with inflammatory polyarthritis who had Hashimoto's thyroiditis were investigated. Only 2/15 had frank myxoedema, 8/15 had incipient hypothyroidism (raised levels of thyrotropin or early symptoms of mild hypothyroidism), and 5/15 were euthyroid (thyrotropin levels normal). The presence or absence of rheumatoid factor (RF) distinguished two subgroups with different se...
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BACKGROUND Severe extra-articular disease is associated with high levels of rheumatoid factor (RF ) in patients with seropositive rheumatoid arthritis (RA ) and a poor prognosis. It is said that patients with seronegative rheumatoid arthritis have a more benign course and less destructive disease. We observed several patients with seronegative non-rheumatoid polyarthritis, with aggressive extra...
متن کاملSeronegative chronic polyarthritis: clinical and serological correlates.
Twenty-seven patients with chronic, active, seronegative polyarthritis were assessed clinically and serologically by accepted criteria for evidence of connective tissue diseases. The patients were divided into 2 groups, 13 positive for fluorescent antinuclear antibody (FANA) and 14 that were negative. All but 1 patient fulfilled the clinical criteria for the diagnosis of definite rheumatoid art...
متن کاملUveitis as a marker of active arthritis in 372 patients with juvenile idiopathic seronegative oligoarthritis or polyarthritis.
OBJECTIVE To compare the activity of arthritis in children with recently diagnosed seronegative oligoarthritis or polyarthritis with or without uveitis. METHODS The study covered 372 JIA children with recently diagnosed seronegative oligoarthritis or polyarthritis. The mean prospective follow-up period was 4.5 years. Asymptomatic anterior uveitis was found in 96 cases. The activity of arthrit...
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Since 1956 biguanides have received attention as oral hypoglycaemic agents (Krall and Bradley, 1959). Ungar, Madison, and Carter (1960), using phenformin (Dibotin, phenethyl biguanide), showed their effect on peripheral utilization of glucose, Butterfield, Fry, and Holling (1958) having previously demonstrated increased uptake of insulin in hepatic and peripheral tissues. Since then the drug ha...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1977
ISSN: 0003-4967
DOI: 10.1136/ard.36.6.593